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Thrombopathia is a blood disorder caused by a dysfunction of platelets, which are responsible for blood clotting.
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Specifiche
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Tampone, Sangue in EDTA, Sangue in Eparina, Seme, Tessuto |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | Calcium-Diacylglycerol Guanine Nucleotide Exchange Factor I (CalDAG-GEFI) |
| Year Published |
Informazioni generali
Thrombopathia is a blood disorder caused by a dysfunction of platelets, which are responsible for blood clotting. This variant of the disease, which is found in the Landseer, is caused by a recessive mutation to the gene RASGRP2. Related variants have been observed in the Basset Hound and the American Eskimo Dog.
Caratteristiche cliniche
I cani affetti sperimentano epistassi (sangue dal naso), sanguinamento delle gengive e petecchiazione sulle mucose e sulla pelle.
Informazioni aggiuntive
Riferimenti
Pubmed ID: 17656327
Omia ID: 2433